BROCHURES / DOCUMENTATION
APPLICATION NOTES
SCIENTIFIC PUBLICATIONS
You are researching: Poly(N-isopropylacrylamide) (PNIPAAm)
Tissue and Organ Biofabrication
Skin Tissue Engineering
Drug Delivery
Biological Molecules
Solid Dosage Drugs
Stem Cells
Personalised Pharmaceuticals
Inducend Pluripotent Stem Cells (IPSCs)
Drug Discovery
Cancer Cell Lines
Cell Type
All Groups
- Printing Technology
- Biomaterial
- Ceramics
- Metals
- Bioinks
- Fibronectin
- Xanthan Gum
- Paeoniflorin
- Methacrylated Silk Fibroin
- Heparin
- Fibrinogen
- (2-Hydroxypropyl)methacrylamide (HPMA)
- Carrageenan
- Chitosan
- Glycerol
- Poly(glycidol)
- Agarose
- methacrylated chondroitin sulfate (CSMA)
- Silk Fibroin
- Methacrylated hyaluronic acid (HAMA)
- Gellan Gum
- Alginate
- Gelatin-Methacryloyl (GelMA)
- Cellulose
- Hyaluronic Acid
- Polyethylene glycol (PEG) based
- Collagen
- Gelatin
- Novogel
- Peptide gel
- α-Bioink
- Elastin
- Matrigel
- Methacrylated Chitosan
- Pectin
- Pyrogallol
- Fibrin
- Methacrylated Collagen (CollMA)
- Glucosamine
- Non-cellularized gels/pastes
- 2-hydroxyethyl) methacrylate (HEMA)
- Paraffin
- Polyphenylene Oxide
- Acrylamide
- SEBS
- Ionic Liquids
- Jeffamine
- Mineral Oil
- Salecan
- Zein
- poly(octanediol-co-maleic anhydride-co-citrate) (POMaC)
- Poly(itaconate-co-citrate-cooctanediol) (PICO)
- Polyvinylpyrrolidone (PVP)
- Salt-based
- Acrylates
- 2-hydroxyethyl-methacrylate (HEMA)
- Magnetorheological fluid (MR fluid – MRF)
- Poly(vinyl alcohol) (PVA)
- PEDOT
- Polyethylene
- Silicone
- Pluronic – Poloxamer
- Carbopol
- Epoxy
- poly (ethylene-co -vinyl acetate) (PEVA)
- Phenylacetylene
- Poly(N-isopropylacrylamide) (PNIPAAm)
- Poly(Oxazoline)
- Poly(trimethylene carbonate)
- Polyisobutylene
- Konjac Gum
- Gelatin-Sucrose Matrix
- Chlorella Microalgae
- Poly(Vinyl Formal)
- Thermoplastics
- Micro/nano-particles
- Biological Molecules
- Decellularized Extracellular Matrix (dECM)
- Solid Dosage Drugs
- Review Paper
- Application
- Tissue Models – Drug Discovery
- BioSensors
- Personalised Pharmaceuticals
- In Vitro Models
- Bioelectronics
- Industrial
- Robotics
- Medical Devices
- Electronics – Robotics – Industrial
- Biomaterial Processing
- Tissue and Organ Biofabrication
- Liver tissue Engineering
- Muscle Tissue Engineering
- Nerve – Neural Tissue Engineering
- Meniscus Tissue Engineering
- Heart – Cardiac Patches Tissue Engineering
- Adipose Tissue Engineering
- Trachea Tissue Engineering
- Ocular Tissue Engineering
- Intervertebral Disc (IVD) Tissue Engineering
- Vascularization
- Skin Tissue Engineering
- Drug Delivery
- Cartilage Tissue Engineering
- Bone Tissue Engineering
- Drug Discovery
- Institution
- Myiongji University
- Hong Kong University
- Veterans Administration Medical Center
- University of Applied Sciences Northwestern Switzerland
- University of Michigan, Biointerfaces Institute
- Sree Chitra Tirunal Institute
- Kaohsiung Medical University
- Baylor College of Medicine
- L'Oreal
- University of Bordeaux
- KU Leuven
- Abu Dhabi University
- University of Sheffield
- DTU – Technical University of Denmark
- Hefei University
- Rice University
- University of Barcelona
- INM – Leibniz Institute for New Materials
- University of Nantes
- Institute for Bioengineering of Catalonia (IBEC)
- University of Amsterdam
- Bayreuth University
- Ghent University
- National University of Singapore
- Adolphe Merkle Institute Fribourg
- Zurich University of Applied Sciences (ZHAW)
- Hallym University
- University of Wurzburg
- AO Research Institute (ARI)
- Chalmers University of Technology
- ETH Zurich
- Nanyang Technological University
- Utrecht Medical Center (UMC)
- University of Manchester
- University of Nottingham
- Trinity College
- National Institutes of Health (NIH)
- Rizzoli Orthopaedic Institute
- University of Bucharest
- Innotere
- Nanjing Medical University
- Ningbo Institute of Materials Technology and Engineering (NIMTE)
- Queen Mary University
- Royal Free Hospital
- SINTEF
- University of Central Florida
- University of Freiburg
- Halle-Wittenberg University
- CIC biomaGUNE
- Chiao Tung University
- University of Geneva
- Novartis
- Karlsruhe institute of technology
- Shanghai University
- Technical University of Dresden
- University of Michigan – School of Dentistry
- University of Tel Aviv
- Aschaffenburg University
- Univerity of Hong Kong
- Chinese Academy of Sciences
- Helmholtz Institute for Pharmaceutical Research Saarland
- Brown University
- Innsbruck University
- National Yang Ming Chiao Tung University
- Tiangong University
- Harbin Institute of Technology
- Montreal University
- Anhui Polytechnic
- Jiao Tong University
- University of Toronto
- Politecnico di Torino
- Biomaterials & Bioinks
- Bioprinting Technologies
- Bioprinting Applications
- Cell Type
- Organoids
- Meniscus Cells
- Skeletal Muscle-Derived Cells (SkMDCs)
- Hepatocytes
- Monocytes
- Neutrophils
- Macrophages
- Corneal Stromal Cells
- Mesothelial cells
- Adipocytes
- Synoviocytes
- Human Trabecular Meshwork Cells
- Epithelial
- Human Umbilical Vein Endothelial Cells (HUVECs)
- Spheroids
- Keratinocytes
- Neurons
- Endothelial
- CardioMyocites
- Osteoblasts
- Articular cartilage progenitor cells (ACPCs)
- Cancer Cell Lines
- Chondrocytes
- Fibroblasts
- Myoblasts
- Melanocytes
- Retinal
- Embrionic Kidney (HEK)
- β cells
- Pericytes
- Bacteria
- Tenocytes
- Stem Cells
AUTHOR
Title
3D printed bioceramics fabricated using negative thermoresponsive hydrogels and silicone oil sealing to promote bone formation in calvarial defects
[Abstract]
Year
2020
Journal/Proceedings
Ceramics International
Reftype
Groups
AbstractThe purpose of the present work was to investigate the potential for application and the effectiveness of osteoconductive scaffolds with bicontinuous phases of 3D printed bioceramics (3DP-BCs) based on reverse negative thermoresponsive hydrogels (poly[(N-isopropylacrylamide)-co-(methacrylic acid)]; p(NiPAAm-MAA)). 3DP-BCs have bioceramic objects and microchannel pores when created using robotic deposition additive manufacturing. We evaluated the benefits of silicone oil sealing on the 3DP-BC green body during the sintering process in terms of densification and structural stability. The shrinkage, density, porosity, element composition, phase structure and microstructural analyses and compression strength measurements of sintered 3DP-BC objects are presented and discussed in this study. In addition, the results of cell viability assays and bone healing analyses of the calvarial bone defects in a rabbit model were used to evaluate 3DP-BC performance. The main results indicated that these 3DP-BC scaffolds have optimal continuous pores and adequate compressive strength, which can enable the protection of calvarial defects and provide an environment for cell growth. Therefore, 3DP-BC scaffolds have better new bone regeneration efficiency in rabbit calvarial bone defect models than empty scaffolds and mold-forming bioceramic scaffolds (MF-BCs).
AUTHOR
Title
A versatile bioink for three-dimensional printing of cellular scaffolds based on thermally and photo-triggered tandem gelation
[Abstract]
Year
2014
Journal/Proceedings
Acta Biomaterialia
Reftype
Groups
AbstractAbstract Layer-by-layer bioprinting is a logical choice for the fabrication of stratified tissues like articular cartilage. Printing of viable organ replacements, however, is dependent on bioinks with appropriate rheological and cytocompatible properties. In cartilage engineering, photocrosslinkable glycosaminoglycan-based hydrogels are chondrogenic, but alone have generally poor printing properties. By blending the thermoresponsive polymer poly(N-isopropylacrylamide) grafted hyaluronan (HA-pNIPAAM) with methacrylated hyaluronan (HAMA), high-resolution scaffolds with good viability were printed. HA-pNIPAAM provided fast gelation and immediate post-printing structural fidelity, while {HAMA} ensured long-term mechanical stability upon photocrosslinking. The bioink was evaluated for rheological properties, swelling behavior, printability and biocompatibility of encapsulated bovine chondrocytes. Elution of HA-pNIPAAM from the scaffold was necessary to obtain good viability. HA-pNIPAAM can therefore be used to support extrusion of a range of biopolymers which undergo tandem gelation, thereby facilitating the printing of cell-laden, stratified cartilage constructs with zonally varying composition and stiffness.