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You are researching: Monocytes
Stem Cells
Personalised Pharmaceuticals
Inducend Pluripotent Stem Cells (IPSCs)
Drug Discovery
Cancer Cell Lines
Cell Type
Tissue and Organ Biofabrication
Skin Tissue Engineering
Drug Delivery
Biological Molecules
Solid Dosage Drugs
All Groups
- Printing Technology
- Biomaterial
- Non-cellularized gels/pastes
- poly (ethylene-co -vinyl acetate) (PEVA)
- Poly(itaconate-co-citrate-cooctanediol) (PICO)
- Poly(N-isopropylacrylamide) (PNIPAAm)
- Mineral Oil
- poly(octanediol-co-maleic anhydride-co-citrate) (POMaC)
- Poly(Oxazoline)
- Poly(trimethylene carbonate)
- 2-hydroxyethyl) methacrylate (HEMA)
- Zein
- Acrylamide
- Pluronic – Poloxamer
- Polyisobutylene
- Paraffin
- Silicone
- Konjac Gum
- Polyphenylene Oxide
- Ionic Liquids
- Polyvinylpyrrolidone (PVP)
- Gelatin-Sucrose Matrix
- Salt-based
- Chlorella Microalgae
- Acrylates
- Poly(Vinyl Formal)
- 2-hydroxyethyl-methacrylate (HEMA)
- Phenylacetylene
- Magnetorheological fluid (MR fluid – MRF)
- Salecan
- Poly(vinyl alcohol) (PVA)
- PEDOT
- Jeffamine
- Poly(methyl methacrylate) (PMMA)
- Polyethylene
- SEBS
- Polypropylene Oxide (PPO)
- Carbopol
- Sucrose Acetate
- Epoxy
- Micro/nano-particles
- Biological Molecules
- Bioinks
- Fibrinogen
- Fibrin
- Paeoniflorin
- Fibronectin
- (2-Hydroxypropyl)methacrylamide (HPMA)
- Methacrylated Collagen (CollMA)
- Carrageenan
- Glucosamine
- Chitosan
- Glycerol
- Poly(glycidol)
- Alginate
- Agarose
- Gelatin-Methacryloyl (GelMA)
- methacrylated chondroitin sulfate (CSMA)
- Cellulose
- Novogel
- carboxybetaine acrylamide (CBAA)
- Hyaluronic Acid
- Peptide gel
- Methacrylated Silk Fibroin
- Pantoan Methacrylate
- Polyethylene glycol (PEG) based
- α-Bioink
- Poly(Acrylic Acid)
- Collagen
- Elastin
- Heparin
- sulfobetaine methacrylate (SBMA)
- Gelatin
- Matrigel
- Gellan Gum
- Methacrylated Chitosan
- Methacrylated hyaluronic acid (HAMA)
- Pectin
- Silk Fibroin
- Pyrogallol
- Xanthan Gum
- Ceramics
- Decellularized Extracellular Matrix (dECM)
- Metals
- Solid Dosage Drugs
- Thermoplastics
- Coaxial Extruder
- Non-cellularized gels/pastes
- Bioprinting Technologies
- Bioprinting Applications
- Cell Type
- Melanocytes
- Retinal
- Chondrocytes
- Embrionic Kidney (HEK)
- Corneal Stromal Cells
- Annulus Fibrosus Cells
- Fibroblasts
- β cells
- Astrocytes
- Myoblasts
- Pericytes
- Hepatocytes
- Cancer Cell Lines
- Bacteria
- Epicardial Cells
- Articular cartilage progenitor cells (ACPCs)
- Tenocytes
- Extracellular Vesicles
- Osteoblasts
- Monocytes
- Mesothelial cells
- Nucleus Pulposus Cells
- Epithelial
- Neutrophils
- Adipocytes
- Smooth Muscle Cells
- T cells
- Human Umbilical Vein Endothelial Cells (HUVECs)
- Organoids
- Stem Cells
- Spheroids
- Meniscus Cells
- Synoviocytes
- Keratinocytes
- Skeletal Muscle-Derived Cells (SkMDCs)
- Neurons
- Macrophages
- Human Trabecular Meshwork Cells
- Endothelial
- CardioMyocites
- Institution
- Trinity College
- Novartis
- University of Central Florida
- Hefei University
- Leibniz University Hannover
- Chalmers University of Technology
- Karlsruhe institute of technology
- University of Freiburg
- Helmholtz Institute for Pharmaceutical Research Saarland
- Leipzig University
- AO Research Institute (ARI)
- Shanghai University
- Univerity of Hong Kong
- University of Toronto
- Brown University
- Polish Academy of Sciences
- University of Wurzburg
- Technical University of Dresden
- University of Nantes
- Montreal University
- Shandong Medical University
- Institute for Bioengineering of Catalonia (IBEC)
- University of Michigan – School of Dentistry
- Myiongji University
- Harbin Institute of Technology
- Technical University of Berlin
- University of Amsterdam
- University of Tel Aviv
- University of Applied Sciences Northwestern Switzerland
- Anhui Polytechnic
- University Children's Hospital Zurich
- Bayreuth University
- Aschaffenburg University
- University of Michigan, Biointerfaces Institute
- Abu Dhabi University
- Jiao Tong University
- University of Aveiro
- Ghent University
- Chiao Tung University
- Sree Chitra Tirunal Institute
- University of Sheffield
- University of Michigan – Biointerfaces Institute
- National University of Singapore
- CIC biomaGUNE
- Kaohsiung Medical University
- DTU – Technical University of Denmark
- University of Taiwan
- Adolphe Merkle Institute Fribourg
- Halle-Wittenberg University
- Baylor College of Medicine
- INM – Leibniz Institute for New Materials
- National Yang Ming Chiao Tung University
- University of Vilnius
- Zurich University of Applied Sciences (ZHAW)
- Innotere
- L'Oreal
- Tiangong University
- Xi’an Children’s Hospital
- ETH Zurich
- Hallym University
- Nanjing Medical University
- University of Bordeaux
- Innsbruck University
- Nanyang Technological University
- National Institutes of Health (NIH)
- Ningbo Institute of Materials Technology and Engineering (NIMTE)
- KU Leuven
- Politecnico di Torino
- Utrecht Medical Center (UMC)
- Rizzoli Orthopaedic Institute
- Queen Mary University
- Veterans Administration Medical Center
- University of Manchester
- University of Bucharest
- Royal Free Hospital
- Hong Kong University
- University of Barcelona
- Chinese Academy of Sciences
- ENEA
- University of Nottingham
- University of Geneva
- SINTEF
- Rice University
- Jiangsu University
- Biomaterials & Bioinks
- Application
- Bioelectronics
- Biomaterial Processing
- Tissue Models – Drug Discovery
- Industrial
- Drug Discovery
- In Vitro Models
- Robotics
- Electronics – Robotics – Industrial
- Medical Devices
- Tissue and Organ Biofabrication
- Heart – Cardiac Patches Tissue Engineering
- Adipose Tissue Engineering
- Trachea Tissue Engineering
- Ocular Tissue Engineering
- Intervertebral Disc (IVD) Tissue Engineering
- Muscle Tissue Engineering
- Liver tissue Engineering
- Cartilage Tissue Engineering
- Bone Tissue Engineering
- Dental Tissue Engineering
- Drug Delivery
- Urethra Tissue Engineering
- Skin Tissue Engineering
- Uterus Tissue Engineering
- Nerve – Neural Tissue Engineering
- Meniscus Tissue Engineering
- BioSensors
- Personalised Pharmaceuticals
- Review Paper
AUTHOR
Title
A 3D multi-cellular tissue model of the human omentum to study the formation of ovarian cancer metastasis
[Abstract]
Year
2023
Journal/Proceedings
Biomaterials
Reftype
Groups
AbstractReliable and predictive experimental models are urgently needed to study metastatic mechanisms of ovarian cancer cells in the omentum. Although models for ovarian cancer cell adhesion and invasion were previously investigated, the lack of certain omental cell types, which influence the metastatic behavior of cancer cells, limits the application of these tissue models. Here, we describe a 3D multi-cellular human omentum tissue model, which considers the spatial arrangement of five omental cell types. Reproducible tissue models were fabricated combining permeable cell culture inserts and bioprinting technology to mimic metastatic processes of immortalized and patient-derived ovarian cancer cells. The implementation of an endothelial barrier further allowed studying the interaction between cancer and endothelial cells during hematogenous dissemination and the impact of chemotherapeutic drugs. This proof-of-concept study may serve as a platform for patient-specific investigations in personalized oncology in the future.
AUTHOR
Title
Multi-Scale Analysis of the Composition, Structure, and Function of Decellularized Extracellular Matrix for Human Skin and Wound Healing Models
[Abstract]
Year
2022
Journal/Proceedings
Biomolecules
Reftype
Groups
AbstractThe extracellular matrix (ECM) is a complex mixture of structural proteins, proteoglycans, and signaling molecules that are essential for tissue integrity and homeostasis. While a number of recent studies have explored the use of decellularized ECM (dECM) as a biomaterial for tissue engineering, the complete composition, structure, and mechanics of these materials remain incompletely understood. In this study, we performed an in-depth characterization of skin-derived dECM biomaterials for human skin equivalent (HSE) models. The dECM materials were purified from porcine skin, and through mass spectrometry profiling, we quantified the presence of major ECM molecules, including types I, III, and VI collagen, fibrillin, and lumican. Rheological analysis demonstrated the sol-gel and shear-thinning properties of dECM materials, indicating their physical suitability as a tissue scaffold, while electron microscopy revealed a complex, hierarchical structure of nanofibers in dECM hydrogels. The dECM materials were compatible with advanced biofabrication techniques, including 3D printing within a gelatin microparticle support bath, printing with a sacrificial material, or blending with other ECM molecules to achieve more complex compositions and structures. As a proof of concept, we also demonstrate how dECM materials can be fabricated into a 3D skin wound healing model using 3D printing. Skin-derived dECM therefore represents a complex and versatile biomaterial with advantageous properties for the fabrication of next-generation HSEs.