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You are researching: Abu Dhabi University
Cell Type
Tissue and Organ Biofabrication
Skin Tissue Engineering
Drug Delivery
Biological Molecules
Solid Dosage Drugs
Stem Cells
Personalised Pharmaceuticals
Inducend Pluripotent Stem Cells (IPSCs)
Drug Discovery
Cancer Cell Lines
All Groups
- Application
- Tissue Models – Drug Discovery
- Tissue and Organ Biofabrication
- Cartilage Tissue Engineering
- Bone Tissue Engineering
- Drug Delivery
- Skin Tissue Engineering
- Vascularization
- Nerve – Neural Tissue Engineering
- Meniscus Tissue Engineering
- Heart – Cardiac Patches Tissue Engineering
- Adipose Tissue Engineering
- Trachea Tissue Engineering
- Ocular Tissue Engineering
- Intervertebral Disc (IVD) Tissue Engineering
- Biomaterial Processing
- Drug Discovery
- Electronics – Robotics – Industrial
- BioSensors
- Personalised Pharmaceuticals
- Bioprinting Technologies
- Biomaterials & Bioinks
- Cell Type
- Organoids
- Meniscus Cells
- Skeletal Muscle-Derived Cells (SkMDCs)
- Macrophages
- Corneal Stromal Cells
- Stem Cells
- Chondrocytes
- Fibroblasts
- Myoblasts
- Cancer Cell Lines
- Articular cartilage progenitor cells (ACPCs)
- Osteoblasts
- Epithelial
- Human Umbilical Vein Endothelial Cells (HUVECs)
- Spheroids
- Keratinocytes
- Neurons
- Endothelial
- CardioMyocites
- Melanocytes
- Retinal
- Embrionic Kidney (HEK)
- β cells
- Pericytes
- Bacteria
- Tenocytes
- Bioprinting Applications
- Institution
- University of Barcelona
- Rice University
- Hefei University
- Abu Dhabi University
- University of Sheffield
- DTU – Technical University of Denmark
- INM – Leibniz Institute for New Materials
- Innsbruck University
- Montreal University
- Harbin Institute of Technology
- ETH Zurich
- Nanyang Technological University
- Utrecht Medical Center (UMC)
- University of Manchester
- University of Nottingham
- Trinity College
- Chalmers University of Technology
- AO Research Institute (ARI)
- University of Wurzburg
- Institute for Bioengineering of Catalonia (IBEC)
- University of Amsterdam
- Bayreuth University
- Ghent University
- National University of Singapore
- Adolphe Merkle Institute Fribourg
- Zurich University of Applied Sciences (ZHAW)
- Hallym University
- National Institutes of Health (NIH)
- Rizzoli Orthopaedic Institute
- University of Bucharest
- University of Geneva
- Novartis
- Karlsruhe institute of technology
- Shanghai University
- Technical University of Dresden
- University of Michigan – School of Dentistry
- University of Tel Aviv
- Aschaffenburg University
- Chiao Tung University
- CIC biomaGUNE
- Halle-Wittenberg University
- Innotere
- Nanjing Medical University
- Ningbo Institute of Materials Technology and Engineering (NIMTE)
- Queen Mary University
- Royal Free Hospital
- SINTEF
- University of Central Florida
- University of Freiburg
- Univerity of Hong Kong
- University of Nantes
- Myiongji University
- University of Applied Sciences Northwestern Switzerland
- University of Michigan, Biointerfaces Institute
- Sree Chitra Tirunal Institute
- Kaohsiung Medical University
- Baylor College of Medicine
- L'Oreal
- University of Bordeaux
- KU Leuven
- Veterans Administration Medical Center
- Hong Kong University
- Review Paper
- Printing Technology
- Biomaterial
- Thermoplastics
- Bioinks
- Xanthan Gum
- Paeoniflorin
- Alginate
- Gelatin-Methacryloyl (GelMA)
- Cellulose
- Hyaluronic Acid
- Polyethylene glycol (PEG) based
- Collagen
- Gelatin
- Gellan Gum
- Methacrylated hyaluronic acid (HAMA)
- Silk Fibroin
- Fibrinogen
- (2-Hydroxypropyl)methacrylamide (HPMA)
- Carrageenan
- Chitosan
- Glycerol
- Poly(glycidol)
- Agarose
- methacrylated chondroitin sulfate (CSMA)
- Novogel
- Peptide gel
- α-Bioink
- Elastin
- Matrigel
- Methacrylated Chitosan
- Pectin
- Pyrogallol
- Fibrin
- Methacrylated Collagen (CollMA)
- Glucosamine
- Non-cellularized gels/pastes
- Jeffamine
- Mineral Oil
- Pluronic – Poloxamer
- Silicone
- Polyvinylpyrrolidone (PVP)
- Salt-based
- Acrylates
- 2-hydroxyethyl-methacrylate (HEMA)
- Magnetorheological fluid (MR fluid – MRF)
- Poly(vinyl alcohol) (PVA)
- PEDOT
- Polyethylene
- Carbopol
- Epoxy
- poly (ethylene-co -vinyl acetate) (PEVA)
- Poly(N-isopropylacrylamide) (PNIPAAm)
- Poly(Oxazoline)
- Poly(trimethylene carbonate)
- Polyisobutylene
- Konjac Gum
- Gelatin-Sucrose Matrix
- Chlorella Microalgae
- Poly(Vinyl Formal)
- Phenylacetylene
- 2-hydroxyethyl) methacrylate (HEMA)
- Paraffin
- Polyphenylene Oxide
- Micro/nano-particles
- Biological Molecules
- Decellularized Extracellular Matrix (dECM)
- Solid Dosage Drugs
- Ceramics
- Metals
AUTHOR
Title
3D printing of complex architected metamaterial structures by simple material extrusion for bone tissue engineering
[Abstract]
Year
2022
Journal/Proceedings
Materials Today Communications
Reftype
Groups
AbstractTriply periodic minimal surfaces (TPMS) are gaining popularity as scaffolds for bioapplications due to their unique structure, offering strong mechanical properties and biomorphic surfaces which enhance cell attachment and proliferation. In this work, polymer TPMS sheet lattices were printed using a well-known yet unprecedented technique of manufacturing such structures; which is material extrusion (specifically, pneumatic melt extrusion). This method offers a one step, straightforward yet reliable way to print complex porous structures while retaining design accuracy and significantly simplifying the process. Multiple primitive, gyroid and cubic structures were designed using MSLattice and Solidworks with 70% porosity and 2×2×3 unit cells. The scaffolds were printed by melt extrusion of polycaprolactone (PCL) at different parameters to establish the optimal settings. Morphological features (pore size and strut thickness) were determined using scanning electron microscopy (SEM) and the accuracy of print was determined by comparing to the design, showing high print accuracy and minimal percentage errors of less than 15% in all prints. Uniaxial compression testing was used to demonstrate the different deformation processes of the scaffolds and evaluate their mechanical properties, with primitive having the highest modulus and gyroid the highest yield strength. Finally, cell viability was quantified by alamar blue cell viability assay and visualized by SEM, displaying significant increase in cell proliferation and attachment, specifically in the primitive structure. Herein we will explain the challenges faced with design and print optimization and how we overcame them, making this work the first of its kind in material extrusion (pneumatic melt extrusion) printing of TPMS scaffolds.
AUTHOR
Title
Bioprinting of bioactive tissue scaffolds from ecologically-destructive fouling tunicates
[Abstract]
Year
2022
Journal/Proceedings
Journal of Cleaner Production
Reftype
Groups
AbstractUrochordates are the closest invertebrate relative to humans and commonly referred to as tunicates, a name ascribed to their leathery outer “tunic”. The tunic is the outer covering of the organism which functions as the exoskeleton and is rich in carbohydrates and proteins. Invasive or fouling tunicates pose a great threat to the indigenous marine ecosystem and governments spend several hundred thousand dollars for tunicate management, considering the huge adverse economic impact it has on the shipping and fishing industries. In this work, the environmentally destructive colonizing tunicate species of Polyclinum constellatum was successfully identified in the coast of Abu Dhabi and methods of sustainably using it as wound-dressing materials, decellularized extra-cellular matrix (dECM) scaffolds for tissue engineering applications and bioinks for bioprinting of tissue constructs for regenerative medicine are proposed. The intricate three-dimensional nanofibrous cellulosic networks in the tunic remain intact even after the multi-step process of decellularization and lyophilization. The lyophilized dECM tunics possess excellent biocompatibility and remarkable tensile modulus of 3.85 ± 0.93 MPa compared to ∼0.1–1 MPa of other hydrogel systems. This work demonstrates the use of lyophilized tunics as wound-dressing materials, having outperformed the commercial dressing materials with a capacity of absorbing 20 times its weight in the dry state. This work also demonstrates the biocompatibility of dECM scaffold and dECM-derived bioink (3D bioprinting with Mouse Embryonic Fibroblasts (MEFs)). Both dECM scaffolds and bioprinted dECM-based tissue constructs show enhanced metabolic activity and cell proliferation over time. Sustainable utilization of dECM-based biomaterials from ecologically-destructive fouling tunicates proposed in this work helps preserve the marine ecosystem, shipping and fishing industries worldwide, and mitigate the huge cost spent for tunicate management.