Shaping the future of healthcare together!

Since 2007, regenHU has dedicated its engineering skills to assist the scientific community with cutting-edge 3D bioprinting solutions.

regenHU’s bioprinters offer a wide selection of high-end professional bioprinting instruments for the driving force of scientific advancements in Tissue Engineering, Regenerative Medicine and Drug Discovery.

Discover ~200 scientific publications using regenHU bioprinters

NEWS | EVENTS

Partners achievements
12.06.2019
Nanyang Technological University Singapore

Layer-by-layer ultraviolet assisted extrusion-based (UAE) bioprinting of hydrogel constructs with high aspect ratio for soft tissue engineering applications

Using the 3DDiscovery’s layer-by-layer UV curing system, researchers at NTU Singapore built thick cell-laden constructs with high shape fidelity and mechanical properties suitable for soft tissue engineering applications.

Sources :
https://doi.org/10.1371/journal.pone.0216776
Authors: Pei Zhuang, Wei Long Ng, Jia An, Chee Kai Chua, Lay Poh Tan

Abstract

One of the major challenges in the field of soft tissue engineering using bioprinting is fabricating complex tissue constructs with desired structure integrity and mechanical property. To accomplish such requirements, most of...


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News
11.11.2019
Press release

regenHU SA appoints Simon MacKenzie as new CEO

Change of leadership at biotechnology company regenHU S.A.

Simon MacKenzie, CEO of regenHU

Swiss investment group Nivalis Group and regenHU’s Board of Directors have unanimously decided to appoint Simon MacKenzie as the new CEO of regenHU S.A. starting 11 November 2019.

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News
03.07.2019
3DPRINT.COM, by Sarah Saunders

Singapore: UV-Assisted Extrusion-Based Bioprinting to Make GelMA Hydrogels for Soft Tissue Engineering

"It’s difficult to manufacture complex tissue constructs with the necessary mechanical properties and structure integrity when you’re with bioprinting in soft tissue engineering. Typically, scientists will use materials, like PCL, to reinforce the inside of 3D bioprinting constructs, but the long degradation period is not great. But a team of researchers – Pei Zhuang, Wei Long Ng, Jia An, Chee Kai Chua, and Lay Poh Tan – from Singapore’s Nanyang Technological University have proposed a novel UV-assisted, extrusion-based (UAE) 3D bioprinting method that could help fabricate soft tissue construc...

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BIOPRINTING SOLUTIONS

3D BIOPRINTERS

– 3DDISCOVERY™ EVOLUTION

– BIOFACTORY™

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BIOMATERIALS

– ECM BIOINK™

– OSTEOINK™

– STARK™

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BIOPRINTING SOFTWARE

– BioCAM™

– BioCAD™

– BioCUT™

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PARTNERS ACHIEVEMENTS

Layer-by-layer ultraviolet assisted extrusion-based (UAE) bioprinting of hydrogel constructs with high aspect ratio for soft tissue engineering applications

Using the 3DDiscovery’s layer-by-layer UV curing system, researchers at NTU Singapore built thick cell-laden constructs with high shape fidelity and mechanical properties suitable for soft tissue engineering applications.

Sources :
https://doi.org/10.1371/journal.pone.0216776
Authors: Pei Zhuang, Wei Long Ng, Jia An, Chee Kai Chua, Lay Poh Tan

Abstract

One of the major challenges in the field of soft tissue engineering using bioprinting is fabricating complex tissue constructs with desired structure integrity and mechanical property. To accomplish such requirements, most of...


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3D Printing of Personalized Thick and Perfusable Cardiac Patches and Hearts

Once again, the flexibility of our technologies is showcased. 3DDiscovery™ Evolution was adapted to FRESH 3D Bioprinting to build vascularized and perfusable cardiac patches.


ABSTRACT : "Generation of thick vascularized tissues that fully match the patient still remains an unmet challenge in cardiac tissue engineering. Here, a simple approach to 3D‐print thick, vascularized, and perfusable cardiac patches that completely match the immunological, cellular, biochemical, and anatomical properties of the patient is reported. To this end, a biopsy of an omental tissue is taken from patients....

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A Stimuli-Responsive Nanocomposite for 3D Anisotropic Cell-Guidance and Magnetic Soft Robotics

"A novel method is presented to biofabricate anisotropic nanocomposite  hydrogels through a mild and biocompatible process driven by multiple  external stimuli: magnetic field, temperature, and light. The  functionality of this stimuliresponsive hydrogel is studied creating i)  3D cell-instructive platforms for in vitro morphogenesis, and ii) a 3D  printable magnetoresponsive ink for fabricating small-scale bioinspired soft robots"

source : Advandced Science News

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SCIENTIFIC PUBLICATIONS

Organomimetic skin model production based on a novel bioprinting technology

Author: Bleisch, Matthias and Kuster, Michael and Thurner, Marc and Meier, Christoph and Bossen, Anke and Graf-Hausner, Ursula

Abstract: In march 2009, the EU commission has introduced new directives. A directive, that foresees a regulatory framework with the aim of phasing out animal testing. It establishes a prohibition to test finished cosmetic products and cosmetic ingredients on animals (testing ban), and a prohibition to market in the European Community of finished cosmetic products and ingredients included in cosmetic products which were tested on animals (marketing ban). Thus, there is an urgent demand by the cosmetic industry for standardized and customized artificial organomimetic skin models for substance testing. Nowadays, human skin models are manually manufactured in cell culture inserts by producing, in a first step, the dermal layer, where fibroblasts are embedded in a collagen I hydrogel. Afterwards, keratinocytes are placed on top of the collagen-embedded fibroblasts to differentiate into the different epidermal layers after an air-lift. These models are rather simple and not reflecting the complexity of native skin (Figure 1). Furthermore, quality control is only possible at the end of the production process, whereas it would be desirable to control the entire process in situ to select for properly built skin models at any time point thereby reducing costs.

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