BROCHURES / DOCUMENTATION
APPLICATION NOTES
SCIENTIFIC PUBLICATIONS
You are researching: Jiao Tong University
Biological Molecules
Solid Dosage Drugs
Stem Cells
Personalised Pharmaceuticals
Inducend Pluripotent Stem Cells (IPSCs)
Drug Discovery
Cancer Cell Lines
Cell Type
Tissue and Organ Biofabrication
Skin Tissue Engineering
Drug Delivery
All Groups
- Review Paper
- Printing Technology
- Biomaterial
- Non-cellularized gels/pastes
- Epoxy
- Poly(itaconate-co-citrate-cooctanediol) (PICO)
- poly (ethylene-co -vinyl acetate) (PEVA)
- Mineral Oil
- poly(octanediol-co-maleic anhydride-co-citrate) (POMaC)
- Poly(N-isopropylacrylamide) (PNIPAAm)
- Poly(Oxazoline)
- 2-hydroxyethyl) methacrylate (HEMA)
- Zein
- Acrylamide
- Poly(trimethylene carbonate)
- Paraffin
- Pluronic – Poloxamer
- Polyisobutylene
- Polyphenylene Oxide
- Ionic Liquids
- Silicone
- Konjac Gum
- Polyvinylpyrrolidone (PVP)
- Gelatin-Sucrose Matrix
- Salt-based
- Chlorella Microalgae
- Acrylates
- Poly(Vinyl Formal)
- 2-hydroxyethyl-methacrylate (HEMA)
- Phenylacetylene
- Salecan
- Magnetorheological fluid (MR fluid – MRF)
- Poly(vinyl alcohol) (PVA)
- Jeffamine
- Poly(methyl methacrylate) (PMMA)
- PEDOT
- SEBS
- Polypropylene Oxide (PPO)
- Polyethylene
- Sucrose Acetate
- Carbopol
- Micro/nano-particles
- Biological Molecules
- Bioinks
- Xanthan Gum
- Silk Fibroin
- Pyrogallol
- Paeoniflorin
- Fibronectin
- Fibrinogen
- Fibrin
- (2-Hydroxypropyl)methacrylamide (HPMA)
- Methacrylated Collagen (CollMA)
- Carrageenan
- Glucosamine
- Chitosan
- Glycerol
- Poly(glycidol)
- Alginate
- Agarose
- Gelatin-Methacryloyl (GelMA)
- methacrylated chondroitin sulfate (CSMA)
- carboxybetaine acrylamide (CBAA)
- Cellulose
- Novogel
- Methacrylated Silk Fibroin
- Pantoan Methacrylate
- Hyaluronic Acid
- Peptide gel
- Poly(Acrylic Acid)
- Polyethylene glycol (PEG) based
- α-Bioink
- Heparin
- sulfobetaine methacrylate (SBMA)
- Collagen
- Elastin
- Gelatin
- Matrigel
- Gellan Gum
- Methacrylated Chitosan
- Methacrylated hyaluronic acid (HAMA)
- Pectin
- Ceramics
- Metals
- Decellularized Extracellular Matrix (dECM)
- Solid Dosage Drugs
- Thermoplastics
- Coaxial Extruder
- Non-cellularized gels/pastes
- Bioprinting Technologies
- Bioprinting Applications
- Cell Type
- CardioMyocites
- Melanocytes
- Retinal
- Corneal Stromal Cells
- Annulus Fibrosus Cells
- Chondrocytes
- Embrionic Kidney (HEK)
- Astrocytes
- Fibroblasts
- β cells
- Hepatocytes
- Myoblasts
- Pericytes
- Epicardial Cells
- Cancer Cell Lines
- Bacteria
- Extracellular Vesicles
- Articular cartilage progenitor cells (ACPCs)
- Tenocytes
- Monocytes
- Mesothelial cells
- Nucleus Pulposus Cells
- Osteoblasts
- Neutrophils
- Adipocytes
- Smooth Muscle Cells
- Epithelial
- T cells
- Organoids
- Human Umbilical Vein Endothelial Cells (HUVECs)
- Meniscus Cells
- Synoviocytes
- Stem Cells
- Spheroids
- Skeletal Muscle-Derived Cells (SkMDCs)
- Keratinocytes
- Macrophages
- Human Trabecular Meshwork Cells
- Neurons
- Endothelial
- Institution
- SINTEF
- Rice University
- Jiangsu University
- University of Nottingham
- University of Geneva
- University of Central Florida
- Hefei University
- Leibniz University Hannover
- Trinity College
- Novartis
- University of Freiburg
- Helmholtz Institute for Pharmaceutical Research Saarland
- Leipzig University
- Chalmers University of Technology
- Karlsruhe institute of technology
- Univerity of Hong Kong
- University of Toronto
- Brown University
- Polish Academy of Sciences
- AO Research Institute (ARI)
- Shanghai University
- University of Nantes
- Montreal University
- Shandong Medical University
- University of Wurzburg
- Technical University of Dresden
- Myiongji University
- Harbin Institute of Technology
- Technical University of Berlin
- Institute for Bioengineering of Catalonia (IBEC)
- University of Michigan – School of Dentistry
- University of Applied Sciences Northwestern Switzerland
- Anhui Polytechnic
- University Children's Hospital Zurich
- University of Amsterdam
- University of Tel Aviv
- University of Michigan, Biointerfaces Institute
- Abu Dhabi University
- Jiao Tong University
- University of Aveiro
- Bayreuth University
- Aschaffenburg University
- Sree Chitra Tirunal Institute
- University of Sheffield
- University of Michigan – Biointerfaces Institute
- Ghent University
- Chiao Tung University
- Kaohsiung Medical University
- DTU – Technical University of Denmark
- University of Taiwan
- National University of Singapore
- CIC biomaGUNE
- Baylor College of Medicine
- INM – Leibniz Institute for New Materials
- National Yang Ming Chiao Tung University
- University of Vilnius
- Adolphe Merkle Institute Fribourg
- Halle-Wittenberg University
- L'Oreal
- Tiangong University
- Xi’an Children’s Hospital
- Zurich University of Applied Sciences (ZHAW)
- Innotere
- University of Bordeaux
- Innsbruck University
- DWI – Leibniz Institute
- ETH Zurich
- Hallym University
- Nanjing Medical University
- KU Leuven
- Politecnico di Torino
- Nanyang Technological University
- National Institutes of Health (NIH)
- Ningbo Institute of Materials Technology and Engineering (NIMTE)
- Veterans Administration Medical Center
- Utrecht Medical Center (UMC)
- Rizzoli Orthopaedic Institute
- Queen Mary University
- Hong Kong University
- University of Barcelona
- Chinese Academy of Sciences
- ENEA
- University of Manchester
- University of Bucharest
- Royal Free Hospital
- Biomaterials & Bioinks
- Application
- Bioelectronics
- Tissue Models – Drug Discovery
- Industrial
- Biomaterial Processing
- In Vitro Models
- Robotics
- Drug Discovery
- Medical Devices
- Electronics – Robotics – Industrial
- Tissue and Organ Biofabrication
- Meniscus Tissue Engineering
- Heart – Cardiac Patches Tissue Engineering
- Adipose Tissue Engineering
- Trachea Tissue Engineering
- Ocular Tissue Engineering
- Muscle Tissue Engineering
- Intervertebral Disc (IVD) Tissue Engineering
- Liver tissue Engineering
- Cartilage Tissue Engineering
- Dental Tissue Engineering
- Bone Tissue Engineering
- Urethra Tissue Engineering
- Drug Delivery
- Uterus Tissue Engineering
- Skin Tissue Engineering
- Nerve – Neural Tissue Engineering
- BioSensors
- Personalised Pharmaceuticals
AUTHOR
Title
Water-responsive 4D printing based on self-assembly of hydrophobic protein “Zein” for the control of degradation rate and drug release
[Abstract]
Year
2023
Journal/Proceedings
Bioactive Materials
Reftype
Groups
AbstractFour-dimensional (4D) printing is a promising technology that provides solutions for compelling needs in various fields. Most of the reported 4D printed systems are based on the temporal shape transformation of printed subjects. Induction of temporal heterogenicity in functions in addition to shape may extend the scope of 4D printing. Herein, we report a 4D printing approach using plant protein (zein) gel inspired by the amyloid fibrils formation mechanism. The printing of zein gel in a specialized layered-Carbopol supporting bath with different water concentrations in an ethanol-water mixture modulates hydrophobic and hydrogen bonding that causes temporal changes in functions. The part of the construct printed in a supporting bath with higher water content exhibits higher drug loading, faster drug release and degradation than those printed in the supporting bath with lower water content. Tri-segment conduit and butterfly-shaped construct with two asymmetrical wings are printed using this system to evaluate biomedical function as nerve conduit and drug delivery system. 4D printed conduits are also effective as a drug-eluting urethral stent in the porcine model. Overall, this study extends the concept of 4D printing beyond shape transformation and presents an approach of fabricating specialized baths for 4D printing that can also be extended to other materials to obtain 4D printed medical devices with translational potential.
AUTHOR
Title
Zein-based 3D tubular constructs with tunable porosity for 3D cell culture and drug delivery
[Abstract]
Year
2023
Journal/Proceedings
Biomedical Engineering Advances
Reftype
Groups
AbstractManufacturing tubular constructs with tunable porosity can mimic the vascular structure, not only for supplying nutrients and removing metabolites to support long-term 3D cell culture but also for delivering bioactive components and drugs to tissues. There are few reports on the second purpose through 3D printing. In this study, bio-inspired tubular constructs with permeability were achieved using zein-based ink, forming structures with tunable porosity via the 3D printing technique. The parameters, e.g., zein content, with/without the addition of porogen, and drying conditions, were optimized to control the porous structure and porosity of the printed tubes. The inner wall of the resultant tube supported the adhesion of endothelial cells. A perfusion system was designed, and the penetrability of zein-based tubular constructs was demonstrated by the dialysis test. Moreover, perfusion of cell culture media and the anti-cancer drug in cell-laden hydrogels with tubular structure resulted in 3-day of 3D cell culture with a higher survival rate, and the drug was delivered to local cells around the tubular constructs, respectively. This is a new report on the preparation of 3D-printed tubular constructs using zein as the biomaterial inks with tunable porosity and porous structure, providing a general system for 3D cell culture, 3D drugs screening/pharmacokinetics in vitro, and tissue engineering.
AUTHOR
Title
Infiltration from Suspension Systems Enables Effective Modulation of 3D Scaffold Properties in Suspension Bioprinting
[Abstract]
Year
2022
Journal/Proceedings
ACS Appl. Mater. Interfaces
Reftype
DOI/URL
DOI
Groups
AbstractBioprinting is a biofabrication technology which allows efficient and large-scale manufacture of 3D cell culture systems. However, the available biomaterials for bioinks used in bioprinting are limited by their printability and biological functionality. Fabricated constructs are often homogeneous and have limited complexity in terms of current 3D cell culture systems comprising multiple cell types. Inspired by the phenomenon that hydrogels can exchange liquids under the infiltration action, infiltration-induced suspension bioprinting (IISBP), a novel printing technique based on a hyaluronic acid (HA) suspension system to modulate the properties of the printed scaffolds by infiltration action, was described in this study. HA served as a suspension system due to its shear-thinning and self-healing rheological properties, simplicity of preparation, reusability, and ease of adjustment to osmotic pressure. Changes in osmotic pressure were able to direct the swelling or shrinkage of 3D printed gelatin methacryloyl (GelMA)-based bioinks, enabling the regulation of physical properties such as fiber diameter, micromorphology, mechanical strength, and water absorption of 3D printed scaffolds. Human umbilical vein endothelial cells (HUVEC) were applied as a cell culture model and printed within cell-laden scaffolds at high resolution and cell viability with the IISBP technique. Herein, the IISBP technique had been realized as a reliable hydrogel-based bioprinting technique, which enabled facile modulation of 3D printed hydrogel scaffolds properties, being expected to meet the scaffolds requirements of a wide range of cell culture conditions to be utilized in bioprinting applications.