Nanyang Technological University Singapore
Layer-by-layer ultraviolet assisted extrusion-based (UAE) bioprinting of hydrogel constructs with high aspect ratio for soft tissue engineering applications
Using the 3DDiscovery’s layer-by-layer UV curing system, researchers at NTU Singapore built thick cell-laden constructs with high shape fidelity and mechanical properties suitable for soft tissue engineering applications.
Authors: Pei Zhuang, Wei Long Ng, Jia An, Chee Kai Chua, Lay Poh Tan
Once again, the flexibility of our technologies is showcased. 3DDiscovery™ Evolution was adapted to FRESH 3D Bioprinting to build vascularized and perfusable cardiac patches.
ABSTRACT : "Generation of thick vascularized tissues that fully match the patient still remains an unmet challenge in cardiac tissue engineering. Here, a simple approach to 3D‐print thick, vascularized, and perfusable cardiac patches that completely match the immunological, cellular, biochemical, and anatomical properties of the patient is reported. To this end, a biopsy of an omental tissue is taken from patients....
AO Research Institute
"A novel method is presented to biofabricate anisotropic nanocomposite hydrogels through a mild and biocompatible process driven by multiple external stimuli: magnetic field, temperature, and light. The functionality of this stimuliresponsive hydrogel is studied creating i) 3D cell-instructive platforms for in vitro morphogenesis, and ii) a 3D printable magnetoresponsive ink for fabricating small-scale bioinspired soft robots"
source : Advandced Science News
"This project has received funding from the European Research Council (ERC) under the: European Union’s Horizon 2020 research and innovation programme (grant agreement No )"
sources: UMC Utrecht
"Markus Rimann hat das Fachgebiet des Bioprinting an der ZHAW aufgebaut. Das Ziel: menschliches Gewebe für eine effiziente Medikamentenentwicklung."
"Markus Rimann am 3D-Bioprinter, der sich hinter der Scheibe in einer sterilen Umgebung befindet. Mit der auf dem Bildschirm geöffneten Software, lässt sich der Drucker steuern."
3D cell culture at Curio Biotech mimicks in vivo conditions.
Curio Biotech is a start-up CRO company providing services to clients ln the lite sciences sector of the pharma, cosmetlc, nutraceutlcal and diagnostic industries.
Curio Biotech constantly improves existing 30 cell culture systems and further develops novel in vitro models.
These novel 30 cell cultures can be used not only for in vitro drug discovery, screening of compounds and pre-clinlcal investigation, but can also be translated for various clinical applications.
In our ageing society, there is a huge medical need for therapies against degenerative muscle and tendon diseases. This study by researchers from ZHAW and Novartis Institutes for Biomedical Research describes a novel drug screening platform with automated production of 3D musculoskeletal-tendon-like tissues, representing a promising tool to address musculoskeletal diseases. Cells and bioink were printed using the 3DDiscovery™ bioprinter, in dumbbell lines designed by regenHU’s integrated BioCAD™ program.
Todays Dental News
Zeynep Aytac works with a 3D-Discovery Bioprinter at the University of Michigan School of Dentistry.